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The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus during sexual stimulation. NO then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine (cGMP) producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.Kamagra Oral Jelly has no direct relaxant effect on isolated human corpus cavernosum but enhances the effect of NO (Nitric oxide) by inhibiting phosphodiesterase type 5 (PDE5) which is for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by Kamagra Oral Jelly causes increased levels of cGMP in the corpus cavernosum resulting in smooth muscle relaxation and inflow of blood to the corpus cavemosum.So buy cheap Kamagra oral jelly 100mg online here.
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